Hydroxypropylkyl methylcelrellose (HPMC), oo ah xarun biyuhu biyo-ku-milma, ayaa si weyn loogu isticmaalaa hagaajinta agab ku saleysan sibidhka. Sida wax lagu daro oo muhiim ah, waxay si weyn u wanaajin kartaa astaamaha jireed iyo kiimikada ee agabyada ku saleysan sibidhka, gaar ahaan marka loo eego hawlgalka, dheecaanka, adhesion iyo hamidda xoojinta alaabada.
1. Hagaajinta dheecaanka walwalka ku saleysan
Cinwaanka sibidhku wuxuu u baahan yahay faro-qaadid wanaagsan inta lagu jiro dhismaha si si habsami leh loogu shubo caaryada oo buuxisa qaabab adag oo adag. Ka dib markii lagu daro hydroxypropyl methylcelrelolose, prote-ka sibidhka wuxuu ilaalin karaa dareeraha wanaagsan sababtuna tahay saamaynta qaro weyn ee qaro weyn. Inta lagu gudajiro, HPMC waxay hagaajin kartaa dareeraha iyadoo la beddelayo codsiga vast ee koollada, si naase uu u nugul yahay waqti dheer oo aan u nuguleyn kala soocidda, kaas oo ku habboon shaqaalaha dhismaha si ay uga shaqeeyaan maaddada.
2. Hagaajinta agabka ku saleysan waxyaabaha ku saleysan sibidhka
Alaabada ku saleysan dareenka sibidhka ayaa muhiim u ah cimrigiisa iyo hagaajinta xoogga. HPMC waa xarun biyuhu biyuhu ku xirneyd oo leh kooxo badan oo biyo-daad ah qaab dhismeedka molikal-ka, taas oo u oggolaanaysa inay si adag ula falgalaan walxaha sibidhka iyo kuwa kale ee buuxiyaha shabakadda. Saamayntani ma fiicnaan karto oo keliya waxqabadka isku xirka inta udhaxeysa sibidhka iyo substrate, laakiin sidoo kale kor u qaadida caabbinta dillaaca iyo digaynta qalabka ku saleysan sibidhka iyo hagaajinta cimrigeenna. Daraasaduhu waxay muujiyeen in agabyada ku saleysan sibidhka ee ay ku daraan HPMC si wax ku ool ah u yareyn karto dilitaanka, diirka iyo danaha, iyadoo kordhinta nolosha adeegga ee maaddada.
3. Hagaajinta saboolka ah ee qalabka ku saleysan sibidhka
Aspreament ee agabyada ku saleysan dareenka ayaa ah mid ka mid ah tilmaamayaasha muhiimka ah ee saameeya cimrigooda. Hordhaca HPMC waxay hagaajin kartaa mic micloshact ee agabyada ku saleysan sibidhka, sameynta qaab dhismeedka shabakadda cufan, sidaasna lagu yareeyo porosity ee sibidhka. Hoos u dhigida Porosity Si toos ah waxay wanaajisaa khamiirka saboolka ah ee agabyada ku saleysan sibidhka. Daraasadaha ayaa muujisay in ku darista qaddar ku habboon HPMC ay si wax ku ool ah uga hortagi karto agabyada ku saleysan sibidhka, yareynta biyaha muddada-dheer, sidaas darteedna ay kor u qaadaan waxqabadka biyuhu ee dhismayaasha.
4. Dib u dhigida hanaanka fuuqmaynta ee sibidhka
Habka fuuqmaynta ee sibidhka waa geedi socod falcelinta kiimikada oo kacsan. Wax soo saarka iyo dhismaha agab ku saleysan sibidhka, heerka falcelinta hawo-mareenka waxay saameyn toos ah ku leedahay waxqabadka ugu dambeeya. Ku darista HPMC ayaa daahi karta habka hawo-mareenka ee sibidhka ee sibidhka ah iyadoo la beddelayo codsashada koollada sibidhka. HPMC waxay si wax ku ool ah u dheereysan kartaa waqtiga shaqada lagana hortagi karaa koollada sibidhka ee si dhaqso leh u adkaanta si dhakhso leh. Muuqaalkaani wuxuu si gaar ah ugu habboon yahay agabyada ku saleysan sibidhka ee u baahan hawlgalka muddada-dheer, kaas oo horumarin kara dabacsanaanta dhismaha iyo hawlgalka agabka.
5. Hagaajinta iska caabbinta qaboojinta ee agabyada ku saleysan sibidhka
Meelaha qabow, agabyada ku saleysan sibidhka waxaa badanaa la soo gaadhsiiyaa wareegga dheecaanka-dhalaalida, kuwaas oo horseedi kara hoos udhaca xoogga agabka iyo burburka dhismayaasha. Ku darista HPMC ee agabyada ku saleysan sibidhka ayaa ka caawiya hagaajinta iska caabinta qaboojiyaha. Iyaga oo yareynaya porosity agabyada ku saleysan sibidhka, HPMC waxay si wax ku ool ah u yareyn kartaa cadaadiska ballaarinta ee biyaha marka ay ka qaboojiso agabyada ku saleysan sibidhka, taas oo ay ku fiicnaato iska caabbinta qaboojiyaha ee qalabka. Daraasadaha ayaa muujiyay in markii xaddiga HPMC lagu daray uu ku habboon yahay, iska caabbinta qaboojiyaha ee agabyada ku saleysan sibidhka, gaar ahaan dhismayaasha ku jira agagaarka qoyan iyo meelaha qabow.
6. Kobcinta caabbinta heerkulka sare ee agabyada ku saleysan sibidhka
Marka qalabka ku saleysan sibidhka ah waxaa loo isticmaalaa jawiga heerkulka sare, had iyo jeer waxay la kulmaan dhibaatooyin ay ka mid yihiin ballaarinta kuleylka iyo foosha, iyo dhimista jirka. Ku darista HPMC waxay hagaajin kartaa iska caabbinta heerkulka sare ee agabyada ku saleysan sibidhka. Maaddaama HPMC ay deggan tahay qaab-dhismeedka kuleylka wanaagsan, waxay ilaalin kartaa qaab dhismeedkeeda kiimikada iyo dhismaheeda jir ahaaneed heerkulka sare, sidaasna loo xoojiyo xoogga iyo cimri dhererka ku saleysan agabyada ku saleysan jawiga heerkulka.
7. Hagaajinta waxqabadka dhismaha
Waxqabadka dhismaha waa mid ka mid ah shuruudaha muhiimka ah ee lagu cabiro tayada agab ku saleysan sibidhka. HPMC si weyn ayey u horumarin kartaa howlgalka agabyada ku saleysan sibidhka oo looga hortago dhibaatooyinka sida kala-baxa iyo qulqulka biyaha inta lagu jiro dhismaha. Markaad codsaneyso, wax ku dhejinaysa ama ku shubida agab ku saleysan sibidhka, soo bandhigida HPMC waxay ka dhigeysaa ashyaado ka wanaagsan iyo waqti-dhimis, si ay u gooyaan kuwa si ku habboon, yareynta dhibaatooyinka ay sababaan qaybinta aan sinnayn ee qalabka dhismaha.
Sida wax lagu daro oo muhiim ah ee agabyada ku saleysan sibidhka, hydroxypropyl methylcelrellalos waxay si weyn u hagaajin kartaa guryaha kaladuwan ee agabka. HPMC waxay muujineysaa wax qabad aad u wanaagsan oo ku saabsan adeegsiga agab ku saleysan sibidhka iyadoo la wanaajinayo dareeraha, adhesion, oo aan la taaban karin, iska caabbinta qulqulka iyo dib-u-dhigista hanaanka hawo-mareenka, gaar ahaan hagaajinta waxqabadka dhismaha iyo cimri-galka. Sidaa darteed, mashaariicda dhismaha ee casriga ah, isticmaalka hydroxypropylyl methrescelrelolose waxay leedahay rajo ballaaran waxayna door wanaagsan ka qaadataa hagaajinta waxqabadka dhameystiran ee qalabka dhismaha.
Waqtiga Post: Febraayo-19-2025