Hydroxypropyl methylcelrelose waa nooc ka mid ah unugyada unugyada inic-ka ee ether ah. Si ka duwan kan loo yaqaan 'metyl methyl peylymeyl cell-ka' crether ', kama falcelin bir bir culus. Sababo la xiriira saamiyada kaladuwan ee chikroxyl iyo hydroxypropyl ee ku jira hydroxypropylylulose methroxypyl-ka, waxaa jira noocyo buluug ah oo hooseeya, halka waxqabadka metrooxyl-ka hooseeya, inta lagu gudajiro nuxurka @droxypropyl. hydroxypropyl bylulose. Si kastaba ha noqotee, nooc kasta oo kala duwan, in kasta oo kaliya oo ah in yar oo ah koox hydroxypropyl ama qayb yar oo ka mid ah methoxyl group-ka kooxda, waxaa jira kala duwanaansho weyn oo xaruuf ku ah xargaha xaaladaha dabiiciga ah ama heerkulka floccle ee xalka aqueolow.
(1) Qalabka fadhiga ee xaruustayaasha hydroxypropyl methylrcellesulose
Xoolaha Hydroxypropyl Mykelrellase ee methroxrexyplopylylulose dhab ahaantii, sidaa darteed waxay leedahay isku mid ah lafta methyl-ka (cellylene), sidaa darteed waxay leedahay unugyada biyaha ee qabow iyo isirka biyaha kulul. Si kastaba ha noqotee, sababtuna tahay kooxda hyroxypropyl, heerkulka gelitaanka ee biyaha kulul ayaa aad uga badan kan methyl bylulose. Tusaale ahaan, dib-u-dhaca ee hydroxypropylylrcelrcellesese xalka aqueous xasaasiyad ku beddelato ds = 0.73 iyo hydroxypropyl ms = 0.43 waa 20 ° C 20 ° C. Sida loo xaliyo xalideeda biyaha, sidoo kale si weyn ayaa loo hagaajiyay. Tusaale ahaan, jajabka hydroxypropyl methylrcellellase (Qaabka grasanular 0.2 ~ 0.5mm at 20 ° C oo ah vicicosity 3pa • si fudud ayaa lagu iibsan karaa biyaha oo aan qaboojin.
Xabfaynta Hydroxypropyl Mykelcouse ee culeyska dabiiciga ah ee ku jirta suuxdinta byroxypropyl methylrcellellase ee ku jirta solvels-ka dabiiciga ah ayaa sidoo kale ka fiican kan methylcellosuse. Metylcelrelose waxay u baahan tahay inay yeelato shahaadada Methoxyl bedelka 2.1 Alaabada kor ku xusan, laakiin waxaa ku jira hydroxypropyl Ms = 1.5 ~ 1.0, oo ah ~ ~ ~ ~ ~ ~ ~ viscodypyplrcyl my methanol oo kor ku badal ah 1.8 1.8, iyo xalalka etmoloddrodry metermos, iyo biyuhu Xoolaha. Waxay sidoo kale ku milmaysaa hydrocarbons chlorogarbons sida methylenene chloride iyo chloroform, iyo solvorm dabiici ah sida acetone, isopropanol iyo aalkolada diaktone iyo diacotol. Xaraashkeeda xabayadiisa dabiiciga ah ayaa ka fiican jilitaanka biyaha.
(2) Sababaha saameyn ku yeelanaya cudurka 'vadroxypropopyl byluyl's Gocod-ka' velcosity preascosity of byroxypropyl 'cluyl melulose waxay la mid tahay kuwa kale ee keligood ah ee keli ah. Waxaa lagu cabiraa 20 ° C oo leh 2% xalka aqueous sida heerka caadiga ah. Muuqaalka isla badeecada wax soo saarku waxay kordhisaa kororka feejignaanta. Alaabada leh miisaanka molikalalbalar ee kaladuwan ee isku-celceliska, sheyga leh miisaanka molika ee weyn ayaa leh viscosity. Xiriirkeeda uu ku leeyahay heerkulka wuxuu la mid yahay kan methyl bylulose. Marka heerkulku kor u kaco, muuqaalku wuxuu bilaabmayaa inuu hoos u dhaco, laakiin marka ay gaarto heerkul gaar ah, viscosity si lama filaan ah ayaa kor u kacda iyo gelistu waxay dhacdaa. Heerkulka jel ee waxyaabaha ka soo baxa viscosity-ka ayaa ka sarreeya. waa mid sare. Dhismaheeda gel kaliya maahan qaboojinta ether, laakiin sidoo kale waxay la xiriirtaa saamiga isku dhafka ah ee methoxyl group iyo kooxda hydroxypropyl iyo tirada guud ee heerka guud ee shahaadada. Waa in la ogaadaa in hydroxypropylylylrcellellase sidoo kale ay tahay paudoudoplastlastic, xallintiisuna waxay xasilloon tahay heerkulka qolka iyada oo aan jirin wax dhib ah oo ka mid ah viscosis-ka mooyee.
(3) Dulqaadashada cusbada ee hydroxypropyl methylcelrelosuse maadaama hyroxypropylylulose methylcelrelose ', ma ahan wax kale oo ka mid ah anshaxa' '' '' '' xalka '' xalka ka falcelinta iont-ka culus ee saqafka ah iyo saadaalin. Cusbada guud sida chloride, broside, fosfooraska, amooniyam, iwm. Ma saadaalin doono markii lagu daro xalka aqueous. Si kastaba ha noqotee, ku darista cusbada waxay leedahay xoogaa saameyn ah ku leh heerkulka floccation ee xalka aqueous. Markii ay kordhayso cusbadu waxay kordhaan, heerkulka gel ayaa hoos u dhacaya. Marka fiirsashada cusbadadu ka hooseyso barta loo yaqaan 'plocquation', viscosity of xalka ayaa kor u kacaya. Sidaa darteed, xaddi badan oo milix ah ayaa lagu daray, iyadoo la codsadaa, waxay ku gaari kartaa saameyn qaro weyn oo dhaqaale ahaan. Sidaa darteed, codsiyada qaarkood, waxaa fiican in loo isticmaalo isku-darka unugyada unugyada unugyada unugyada iyo milix ee aad u sarreyso xalka sare ee xalka Ether si loo gaaro saameynta dhumucda.
(4) Hydroxypropylkylcellellase playlcelrellase acid iyo iska caabbinta Alkali Hydroxypropylyl Mykelcelrelolose guud ahaan waxay ku xasilloon tahay aashitada iyo alkalis, oo aaney saameyn ku lahayn tirada Ph 2 ~ 12. Waxay u adkeysan kartaa qaddarka khafiifka ah ee iftiinka, sida aashitada qaabeeya, aashitada aashitada, citric acid, sunta acid, phosphoric acid, iwm. Laakiin aashitada ku urursan, iwm. Alkalis sida soodhada cagaha, caustic potash iyo liin biyo ma leh wax saameyn ah kuma laha, laakiin waxyar ayey kordhin karaan qaboojinta xalka, ka dibna si tartiib tartiib ah ayey u yareeyaan.
(5) Niyad jabka hydroxypropylylulolose methroxsypelrelosus hydroxypropylypellellalose metmylcelrellose xalka waxaa lagu qasi karaa xeryo-bolmer-ka-biyo-ku-laabashada biyaha si loo noqdo isku-xirnaan iyo taam ah oo ku saabsan viscosity iyo transpress Xogtan polymer-ka ah waxaa ka mid ah polyvylen glycol, polyvinyl acetate, polysilicone, polymethylvinyllvinyl, hydroxyetyl cellulose, iyo melulose cellyl. Xirmooyinka Moleculal ee Sare ee Dabiiciga ah sida ciridka ciridka, xanjada digaagga abu, xanjo Karada, iwm. Hydroxypropylylrcellellalose sidoo kale waxaa lagu qasi karaa mannitol ester-ka Mannitol ama sirtol acids-ka ama palmitol acid, iyo unugyadan waxaa loo isticmaali karaa sida biyo-xireennada metroxypropyl.
(6) Qeybta unugyada biyaha-lagu milato ee ku-meel-gaarka ah ee ku-meel-gaarka ah ALDEHYDES oo sameeya hydroxypropylyl metylcelrelose waxaa ka mid ah Formaldyde, gelcinic aldehyde, iwm. Qiyaasta wakiilka noocan oo kale ah ee iskutallaabta xalka ah waa 0.2% ~ 10% tirada badan ee Etter, doorbida 7% ~ 10%, tusaale ahaan, 3.3% ~ 6% gellical waa kuwa ugu habboon. Guud ahaan, heerkulka daweynta waa 0 ~ 30 ℃, oo waqtiguna waa 1 ~ 120min. Fal-celinta iskutallaabta ayaa loo baahan yahay in lagu qaado xaaladaha aashitada. Guud ahaan, pH ee xalka waxaa lagu hagaajiyaa ilaa 2 ~ 6 adoo ku daraya inorganic acid add acid ama shey dabiici ah oo ah xalka, doorbidayaa inta u dhaxaysa 4 ~ 6, ka dibna aldehydes-ka ayaa lagu daray si ay u fuliyaan falcelinta iskutallaabta. Aashitada loo isticmaalo ayaa leh hydrochloric acid, aashitada sulfrictoric, phosphoric acid, acid acid, acetic acid-acid, oo acid acid ama acetic acid ayaa lagu talinayaa, oo and and and and and and and and and and and and and and and and and and and and and and and and and acid 'waa mid fiican. Asiidhka iyo aldehyde sidoo kale waa lagu dari karaa si isku mid ah si loogu oggolaado xalka si loo maro falcelin isgoys ah oo isku xira oo ka dhex jira xadka PH ee la doonayo. Fal-celintaan waxaa badanaa loo isticmaalaa geedi socodka daaweynta ugu dambeysa ee habka diyaarinta ee anshaxa qalliinka ee keli ah. Ka dib markii cellinka chether uu kacsan yahay, way ku habboon tahay in la isticmaalo.
20 ~ 25 ℃ biyaha dhaqitaanka iyo nadiifinta. Marka sheyga la isticmaalo, walxaha alkaline waxaa lagu dari karaa xalka sheyga si loo habeeyo pH ee xalka xalka, iyo sheygu si dhakhso ah ayuu u milmi doonaa xalka. Qaabkan ayaa sidoo kale lagu dabaqi karaa daaweynta filimka ka dib markii unugyada unugyada loo yaqaan 'Ether Ether' loo sameeyo filim si looga dhigo filim aan ka dhigin.
(7) Cadaadiska enzyme ee hydroxypropylylrcellellase waa mid asal ahaan ka samaysan oo ah koox-xireenno ah, haddii ay jirto in qiimahoodu ka badalo 1, waxay sidoo kale ku xadgudbi doontaa enzymes, taas oo macnaheedu yahay in heerka beddelka lagu beddelo. Koox kasta oo ka mid ah silsiladda unugyada ma aha isku mid ah, iyo sheybaarka microodds-ka ayaa ku burburin kara kooxda ANHYROGrogluse-ka aan la-tagi karin si ay u sameeyaan sokorta, sida nafaqada loogu talagalay sheyga si uu u nuugo. Sidaa darteed, haddii heerka ka beddelka ku beddelashada unugyada kanuga uu kordho, caabbinta nabaad-guurka nabaad-guurka unugyada unugyada unugyada laf-dhabarka ayaa sidoo kale kordha. Marka loo eego warbixinnada, xaaladaha la xakameeyo, natiijooyinka hydrolysis ee enzymes-ka ayaa la sameeyay, jawiga haraaga ah ee hydroxypelrelosuse (DS = 1.86) waa 1.8%, iyo 1.66) waa 3.8%, iyo hydroxyetyl cellule waa 1.7%. Waxaa lagu arki karaa in hyroxypropyl methylcelrelose uu leeyahay awood anti-enzyme oo xoog badan. Sidaa darteed, caabbinta enzyme ee wanaagsan ee hydroxypropylylrcellellase methylrcellellase, oo ay weheliso guryahooda wanaagsan, oo lagu daray guryaha, iyo filimka sameynta iyo filimka, iyo guud ahaan uma baahna in lagu daro waxyaabaha lagu keydiyo. Si kastaba ha noqotee, kaydinta muddada-dheer ee xalka ama faddaraynta suurtagalka ah ee ka soo baxa dibedda, waxyaabaha lagu keydiyo waxaa lagu dari karaa si ka hortag ah, xulashada waxaa lagu go'aamin karaa iyadoo loo eegayo shuruudaha ugu dambeeya ee xalka. Phenylmercuric acetate iyo manganese folorosalete waa kuwa wax ku ool ah oo wax ku ool ah, laakiin dhammaantood waxay leeyihiin sun sun ah, fiiro gaar ah waa in la siiyaa hawlgalka. Guud ahaan, 1 ~ 5mg ee phenylmersycess acetate waxaa lagu dari karaa xalka halkii litir ee qiyaasta.
(8) Waxqabadka Hydroxypropyl Mydylcellellase Filimka hyroxypropyl methylcelrelosuse wuxuu leeyahay filim-guud oo filim ah oo wanaagsan. Xalkeeda aqueous ama xalka dareeraha dabiiciga ah waxaa lagu daboolaa saxan galaas ah, oo waxay noqotaa midab la'aan iyo daahfurnaan ka dib qalajinta. Iyo filim adag. Waxay leedahay iska caabin qoyan oo wanaagsan oo weli ku adag heerkulka sare. Haddii lagu daro balli-ga hygroscopizer, dalaggiisa iyo dabacsanaantiisa waa la xoojin karaa. Marka laga hadlayo hagaajinta dabacsanaanta, balacayaasha sida Glycerin iyo Sortol ayaa ah kuwa ugu habboon. Guud ahaan, uruurinta xalka waa 2% ~ 3%, iyo qadarka baladizer-ka waa 10% ~ 20% oo ka mid ah celter celther. Haddii nuxurka caaga-balaastik uu aad u sarreeyo, hoos udhaca fuuq-baxa fuuq-baxa wuxuu ku dhici doonaa huurka badan. Awoodda togan ee filimka oo ay ku jiraan balastar-ka ayaa aad uga ballaaran kan aan lahayn balakool, waxayna ku kordheysaa kororka qaddarka lagu daray. Sida loogu talagalay hygroscopicity filimka, waxay sidoo kale kordhisaa kororka qaddarka balaala-yaqaanka.
Waqtiga Post: Jun-13-2023